Liver failure
نویسندگان
چکیده
منابع مشابه
Liver Failure and Liver Disease
Cirrhosis with ascites is associated with impaired renal function accompanied by sodium and water retention. Although it has been suggested thatmediators such as nitric oxide play a role in the development of renal failure in this situation, other mechanisms underlying the process are not well understood. This study examined the role of oxidative stress in mediating renal damage during the deve...
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Severe acetaminophen hepatotoxicity frequently leads to acute liver failure (ALF). We determined the incidence, risk factors, and outcomes of acetaminophen-induced ALF at 22 tertiary care centers in the United States. Detailed prospective data were gathered on 662 consecutive patients over a 6-year period fulfilling standard criteria for ALF (coagulopathy and encephalopathy), from which 275 (42...
متن کاملPost-hepatectomy liver failure.
Hepatectomies are among some of the most complex operative interventions performed. Mortality rates after major hepatectomy are as high as 30%, with post-hepatic liver failure (PHLF) representing the major source of morbidity and mortality. We present a review of PHLF, including the current definition, predictive factors, pre-operative risk assessment, techniques to prevent PHLF, identification...
متن کاملClopidogrel-induced liver failure
The thienopyridine derivative clopidogrel (CPG) inhibits ADP-induced platelet activation. It is rapidly hydrolysed in the liver via cytochrome P450 enzymes, by an irreversible and NADPHdependent mechanism. Clopidogrel therapy is indicated in the prevention of thrombotic events in patients with acute coronary syndromes, ischemic stroke and peripheral arterial disease or after percutaneous stent ...
متن کاملAcute liver failure.
Acute liver failure in children is associated with a high mortality. Most cases in our setup are due to water borne hepatotropic viruses HAV and HEV. The clinician must be aware of the earliest and the subtle signs of acute liver failure to identify cases early enough and institute supportive therapy. Focus of therapy has to be on prevention, early recognition and appropriate management of comp...
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ژورنال
عنوان ژورنال: Gut
سال: 1987
ISSN: 0017-5749
DOI: 10.1136/gut.28.1.112-b